Biographical sketch:

Matthias studied chemistry at the Karlsruhe Institute of Technology (KIT; Germany), the Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM; France), and the University of Heidelberg (Germany). He obtained his doctorate from the University of Tübingen (Germany) where he worked in the group of Prof. Stefan Laufer on reversible and irreversible inhibitors of the protein kinase JAK3. As a postdoc at the Swiss Federal Institute of Technology (ETH) Zürich (with Prof. Karl-Heinz Altmann), he focused on the total synthesis of complex natural products from the mycolactone family. In 2019, he was appointed as Assistant Professor for Medicinal Chemistry at the Institute of Pharmaceutical Sciences, University of Tübingen, and Associate Investigator in the Cluster of Excellence “Image Guided and Functionally Instructed Tumor Therapies (iFIT)”. In May 2024, he was appointed as Full Professor and head of the Division for Medicinal Chemistry at the Institute of Biomedical Engineering of the Faculty of Medicine, University of Tübingen. His research in the areas of Medicinal Chemistry and Chemical Biology focuses primarily on covalent protein kinase inhibitors and novel approaches for the covalent targeting of cysteine and other amino acids. He received a variety of awards including the Young Investigator Award of the German Pharmaceutical Society and very recently the Phil Portoghese Lectureship Award of the American Chemical Society MEDI division.

Publications

ORCID